Drug Discovery News
August 2024
Behind the podcast: Sounding off in a nuclear reactor
July 2024
Restoring color vision with gene therapy
Science stands on shaky shoulders with research misconduct
Profiling the spatial secrets of the placenta
June 2024
The robots making cell therapies
May 2024
Moderna’s path to mRNA therapies for rare metabolic disorders
April 2024
All about location for mRNA translation
A live bacteria treatment for acne
Treating antibiotic resistant infections with amoeba
March 2024
Don’t sleep on storytelling in science
January 2024
A new computational tool predicts drug targets and side effects
Powering up natural killer cells to fight cancer
3D bioprinting tissues in space to heal people on Earth
From COVID-19 to TB, mucosal vaccines stop infections before they start
December 2023
No more daily pills: A new star in long-acting drug delivery
November 2023
Deadly alcoholic hepatitis finds hope in epigenetics
Musical medicine for Parkinson’s disease
Filtering out cancer’s invisibility cloak
When happy accidents lead to new discoveries
October 2023
Lighting up tuberculosis with point-of-care diagnostics
With a boost from beta, alpha thalassemia gene therapies blossom
September 2023
Targeting microbes to treat heart disease
Mini and monstrous mitochondria may contribute to deafness
August 2023
Neonatal drug development comes out of the Dark Ages
What the mifepristone fight means for drug development
From sea monkeys to shelf-stable insulin
July 2023
Shadowing SARS-CoV-2 infections through mucus and cilia
From the cancer research bench to the vascular disease bedside
June 2023
Immunotherapy implants turn brain tumors against themselves
An in utero stem cell transplant for alpha thalassemia
May 2023
Tardigrades protect proteins on the brink of death
April 2023
Arming bacteria with diarrhea-fighting nanobodies
Sniffing out cancer with animal noses
Switching on safer CAR T cell therapy
Treating cancer with a dose of the pox
March 2023
No need for a cold chain with these thin films
A conference and a COVID-19 close call
The path to treating Parkinson’s disease begins in the gut
Better rabies treatments bite back
Origami vaccines fold up to fight cancer
February 2023
Drops and drugs for diabetic vison loss
From dye to base editing, early aging may soon have a cure
January 2023
A nasal algae vaccine against malaria
Worm-associated bacteria are an untapped source of antibiotics
Mining human proteins for hidden antibiotics
December 2022
Glass T cells kill cancer in living color
November 2022
Sequencing 100,000 genomes to revolutionize Nigerian genomics
Heart cells grow to their own beats
For neurological disorders, milk-based therapies are on the way
Delivering smart solutions for osteoarthritis
3D genomics reveals targets for aggressive childhood cancers
October 2022
Viral reactivation may cause CAR T cell-induced neurotoxicity
Infusing CRISPR therapeutics with safety and soul
Tattoo therapeutics deliver medicine more than skin deep
September 2022
Lipoproteins hide Lyme bacteria from the immune system
Missing mutations solve a genetic mystery
Science comedy gets to the heart of science communication
Explainer feature: What the pox is going on?
July/August 2022
Metabolomics open a window into better cancer treatments
Predicting immune responses to vaccination
Menstrual blood holds the key to better diagnostics
Bacterial nanosyringes are drug and delivery all in one
June 2022
Self-amplifying RNA may reduce side effects associated with RNA vaccines
A “morning-of” pill for on-demand contraception
An infective spark for Alzheimer’s disease
Infographic: Next-generation nanoparticle delivery
Human-mouse hybrids accelerate nanoparticle discovery
Gut microbes may predict the effectiveness of anthelminthic drugs
May 2022
Goodbye biopsies, non-invasive diagnostics for fatty liver disease are here
Shrinking toys inspire diagnostics and wearable sensors of the future
Safer eye floater treatments come with a burst of nanobubbles
Scientific research is a series of infinite mysteries
April 2022
A microbial signal from the gut promotes obesity
A pandemic lost in translation
Epithelial cells use immune proteins to find and remove precancerous cells
A new weight loss strategy turns fat into energy
Snakebite antivenoms step into the future
Brain cancer meets its match with focused ultrasound treatment
March 2022
The quest for a respiratory syncytial virus vaccine is almost complete
Ultra-rare childhood fevers are no match for this scientist
Opportunity and teamwork lead to new staph infection treatments
Scientists developed a vaccine targeting all mosquito-transmitted diseases
February 2022
Scientists investigate the COVID-19 vaccine-menstruation mystery
Expanding the genetic code with quadruplet codons may lead to new drugs
Invisible pandemics persist alongside COVID-19
January 2022
A viral decoy blocks cancer cell proliferation
From superfood to medicine maker, spirulina is a new cellular factory
Warring fungi produce new drugs for cancer and infectious disease
Animal microbiomes hold the key to new antifungals
Sea cucumbers and starfish reveal the secrets of stem cells and regeneration
Aloe vera may soothe bladder pain
December 2021
Salamanders hold the secrets to limb regeneration
November 2021
Meet the microrobots primed to take down cancer
Ivermectin is a wonder drug, but not a cure-all
Tracking autism from birth to diagnosis with the microbiome
October 2021
Fish skin heals the toughest wounds
A new molecule disrupts tuberculosis by cutting off cholesterol
A neurosteroid hope for postpartum depression
Decoding cell behavior and disease with AI and single-cell transcriptomics
Chagas disease is an invisible heartache that preventative screening can heal
Harnessing cells’ own RNA editing tools for new therapeutics
Targeting gut bacteria to treat autism
September 2021
A live parasite vaccine for deadly leishmaniasis
Prescribing art therapy for Parkinson’s disease
CAR T cell therapy gives glioblastoma patients hope
July/August 2021
Skin cells use epigenetics to tolerate microorganisms
Keolu Fox revises historical narratives with genome data
Depleting skin immune cells helps treat cutaneous lupus
A shark antibody shuttles neuroprotection across the blood brain barrier
Infographic: Hitchhiking Microbes
Keeping astronauts healthy in space
Space alters an astronaut’s immune system
June 2021
A small molecule inhibitor blocks breast cancer’s back up plan
Activating a brain circuit relieves pain in male mice, but not in female mice
Can a probiotic prevent type 1 diabetes in children?
May 2021
Light and sound stimulation improves early Alzheimer’s disease symptoms
You Have Your Mother’s Eyes — and Cells
Killing Cancer Cells by Stressing Them Out
Hibernating animals may help cure complex human disease
Platelets Take Down Bacteria with the Help of a Trusty Anti-Viral
A New Tool called Rewind Finds Rare Cells Primed for Drug Resistance
Scientists Repurposed an Orphan Drug to Kill Blood-Feeding Tsetse Flies
Discover Magazine
How Science Is Saving Van Gogh’s Flowers Before They Fade Away (May 2021)
Quanta Magazine
A New Algorithm for Graph Crossings, Hiding in Plain Sight (September 2020)
The Los Angeles Times
Column One: Doctor-poets search for the right words to help patients heal
Ocean robots take the pulse of our planet by measuring microbes
Bones pulled from the La Brea Tar Pits show the perils of being a picky eater
Everything you need to know about toxic algae blooms
Gender gap in STEM fields could be due to girls’ reading skills, not math ability
210,000-year-old skull in Greece is earliest sign of modern humans in Europe or Asia
Trees could reduce carbon in the atmosphere to levels not seen in nearly 100 years
Archaeologists have a new way to unlock the secrets of ancient burned bones
Marathon runners get a boost from the bacteria in their guts
Experiment with ‘lost’ wallets reveals that people are surprisingly honest
EpiBeat
Frog Eyes Might Be the Key to Retinal Regeneration
The Beneficial Effect of Exercise on DNA Methylation
Up All Night and Asleep All Day: How Jet Lag Impacts Epigenetics
How a C. elegans Histone Methyltransferase Targets Regions to Silence
Hidden in Plain Sight: How Altering Heterochromatin Disguises Malaria from its Host
An Epigenetic Link to Recurrent Miscarriage
MicroRNAs Team Up to Take Down Brain Cancer
Losing Heterochromatin to Determine Cell Fate
Ripening Oranges with Epigenetics
Low HDAC3 Expression Leads to Endometriosis-Linked Infertility
Untangling the Role of Tau on the Epigenome of Alzheimer’s Brains
Cellular Antivirus: How Foreign DNA is Hushed
Implicating Methylation Variability in Depression
A Flash-Frozen View of Condensing Chromatin
HDAC Inhibitor Stops HPV in its Tracks
Balancing Bones: Epigenetic Regulators Are Important for Maintaining Bone Homeostasis
Mapping the Chromatin Landscape of Cancers
A Role for Histones in Paternal Epigenetic Inheritance
A Simultaneous Picture of Gene Expression and Chromatin Landscape in Single Cells
Aging Promotes Tissue Regeneration and Less Scar Formation
Signal to Noise Magazine
A Burst of Blue Thousands of Years in the Making
Constellations: A Play of Multiple Universes and Infinite Possibilities
Tales of Trailblazing Women in Science
Calling a Microscopic Quorum: How Fungi Communicate
Of Spies and Space-Time: The Science Behind Marvel’s Agent Carter
Stabilizing the Blood-Brain Barrier Against Invading Parasites
When Viruses and Carbon Nanotubes Collide: A Novel Approach to Cancer Imaging
Stephanie DeMarco -- Science Writer 